University of Texas at Austin
Center for Computational Life Sciences and Biology

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Open Position in Our Lab: Deep Learning for Structural Biology 

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Center for Computational Life Sciences and Biology

Computational Structural Biology

Our research group is at the forefront of developing a new generation of computational tools that integrate physics, artificial intelligence, and computational biology to transform drug design. We focus on two primary goals: developing mathematically elegant deep learning architectures that incorporate physical principles to model macromolecular structure and function at the genome scale, and applying these approaches to design therapeutic molecules with precise biological properties. By explaining disease mechanisms at the molecular level, our work aims to accelerate the drug discovery process, reduce costs, and unlock new possibilities for targeting complex conditions, particularly difficult-to-treat cancers.

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Open Position in Our Lab: Deep Learning for Structural Biology

We are inviting highly qualified undergraduate or graduate students to join our research group at the Oden Institute, University of Texas at Austin. This is a competitive opportunity for individuals with proven deep learning expertise and a strong interest in pioneering applications in computational biology.

About Our Work 
Our lab is internationally recognized in molecular and structural modeling, with a focus on structure prediction. We are developing next-generation deep learning architectures that have outperformed models like AlphaFold3 and Boltz in benchmark evaluations. Our success has been validated in blind prediction challenges such as CASP16, CAPRI, and other international competitions. We integrate physical and biological insights with the latest advances in machine learning to accelerate drug discovery and tackle critical challenges in molecular biology. Our research is funded by CPRIT (Cancer Prevention and Research Institute of Texas), MD Anderson Cancer Center, and several leading pharmaceutical companies. These collaborations support ambitious, interdisciplinary projects with clear biomedical impact.

Ideal Candidate Profile 
We are looking for individuals with:   

  • Strong experience in deep learning, especially in:
    • Geometric Deep Learning
    • Diffusion Models
    • Related areas such as graph neural networks, equivariant architectures, and generative modeling
  • Proficient programming skills and familiarity with modern machine learning frameworks
  • Interest or background in biological or structural applications (preferred but not required)

 

Why Join Us   

  • Be part of a globally competitive lab at the forefront of AI and biology
  • Contribute to projects with real-world applications in healthcare and drug design
  • Collaborate with a multidisciplinary team of experts in computational biology, machine learning, and biophysics
  • Gain hands-on experience in validating AI-driven discoveries through partnerships with experimental labs

 

We welcome motivated individuals eager to work in a dynamic and impactful research environment. If this aligns with your interests and background, we encourage you to apply by emailing ernestglukhov@my.utexas.edu (please also CC dima.kozakov@oden.utexas.edu).

News in brief

5 Questions for Dima Kozakov

News

Oct. 15, 2025

5 Questions for Dima Kozakov

Dima Kozakov, recently recruited to UT Austin’s Oden Institute and College of Natural Sciences, is leading a new research center focused on integrating AI and physics into drug discovery. His team aims to revolutionize cancer therapeutics by developing physics-aware AI models that accelerate personalized treatment design and translation into clinical impact.

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UT Faculty Receive Texas Grants Igniting Research Innovation

News

Sept. 29, 2025

UT Faculty Receive Texas Grants Igniting Research Innovation

Charles Taylor and Dima Kozakov are recipients of major grants from the State of Texas. Taylor received the Governor’s University Research Initiative (GURI) grant, and Kozakov received a grant from the Cancer Prevention and Research Institute of Texas (CPRIT).

 

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