Tension between research and clinical practice in medicine
Tuesday, June 27, 2017
1PM – 2PM
The U.S. spends approximately five times more per person in health care costs than countries with a similar life expectancy. These expenditures largely compensated for diagnostic tests and therapeutic interventions. Thus increase in tests and interventions does not translate into improvement in health outcomes. The predictive value of the diagnostic tests and net benefit of interventions for an individual are driven by the baseline risk of the disorder. We propose to develop risk prediction models of adverse health outcomes which will allow calculation of individual prior probabilities of disease and thus the determination of the individual predictive value of the diagnostic tests and net benefits of interventions. These individual prior probabilities will, in turn, become an integral part of Bayesian Medical Decision Making engine.
Dr. Radek Bukowski is Professor and Associate Chair for Investigation and Discovery in the Department of Women's Health. He came to Dell Medical School from the Yale University, where he was a Professor of Obstetrics, Gynecology and Reproductive Sciences and Director of the Division of Maternal Fetal Medicine at Yale School of Medicine, and Chief of Maternal Fetal Medicine at the Yale-New Haven Hospital. He completed medical school and OB/GYN residency at the University of Poznan in Poland and received his Ph.D. from the Freie Universitaet Berlin. He then completed a second residency at the Eastern Virginia Medical School and a fellowship in Maternal Fetal Medicine at the University of Texas Medical Branch at Galveston. Dr. Bukowski was a faculty in the Division of Maternal Fetal Medicine at the University of Texas Medical Branch at Galveston for 16 years achieving the rank of tenured Professor of Obstetrics and Gynecology. Dr. Bukowski's research focuses on health risk prediction, preterm birth, stillbirth, developmental programming, and long-term health consequences of adverse outcomes of pregnancy. His publications have appeared in numerous high impact journals including the New England Journal of Medicine, the Journal of the American Medical Association (JAMA), PLoS Medicine and the British Medical Journal. Dr. Bukowski's work has been supported by six NIH grants. He is an internationally recognized expert in Maternal Fetal Medicine, receiving numerous awards including the prestigious March of Dimes award for Best Research in Prematurity.
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