Monday, February 28, 2PM
Since their discovery in the 20th century, antimicrobial drugs (for example, antibiotics) have substantially reduced the threat of infectious diseases. These gains are now jeopardized by the emergence and spread of microbes that are resistant to the drugs. I'll describe how protein design algorithms, from the new field of computational synthetic biology, can provide tools to combat drug resistance. Experimental results, and a straightforward, but intriguing connection to game theory will be shown.
Images: http://www.cs.duke.edu/~brd/Images/pnas10-xtal-mutant1.jpg http://www.cs.duke.edu/~brd/Images/Lab/brd_class_rot.png
Refreshments served at 1:45 pm
Host: R. Elber