Facebook IconTwitter IconLinkedIn IconFlickr IconYouTube IconRSS Feed Icon
 |  
sysnet • webmail • admin

Anticipating Resistance

Monday, February 28, 2PM
POB 6.304

Bruce Donald

Since their discovery in the 20th century, antimicrobial drugs (for example, antibiotics) have substantially reduced the threat of infectious diseases. These gains are now jeopardized by the emergence and spread of microbes that are resistant to the drugs. I'll describe how protein design algorithms, from the new field of computational synthetic biology, can provide tools to combat drug resistance. Experimental results, and a straightforward, but intriguing connection to game theory will be shown.

Article: http://www.pnas.org/content/107/31/13707.abstract

Images: http://www.cs.duke.edu/~brd/Images/pnas10-xtal-mutant1.jpg http://www.cs.duke.edu/~brd/Images/Lab/brd_class_rot.png

Refreshments served at 1:45 pm

Host: R. Elber